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Excedrin is an over-the-counter headache pain reliever, typically in the form of tablets or caplets. It contains paracetamol (acetaminophen), aspirin, and caffeine. Until late 2005 it was manufactured by Bristol-Myers Squibb, but in July 2005 it was purchased by (and is now produced by) Novartis, along with other products from BMS's over-the-counter business. Excedrin was one of the top ten selling over-the-counter medicine brands in the United States.〔(【引用サイトリンク】work=Daily Mail )〕 There are other brands on the market that contain the same combination of drugs, such as the Roter APC tablets available in Europe. The brand became known for advertisements in which Excedrin cured especially unpleasant and excruciating headaches (which were termed in the advertisements as "Excedrin headaches," later called "Excedrin tension headaches"). In 2007, the brand branched out into marketing for other types of pains with the introduction of Excedrin Back & Body, which removed the caffeine from the normal mixture. ==Versions== Over the years, different types of the drug were introduced:〔(【引用サイトリンク】work=BMS News )〕〔(【引用サイトリンク】date=Nov 12, 2006 )〕 * 1960 Excedrin Extra Strength (the formula changed for the last time in 1978)〔(【引用サイトリンク】work=BMS News )〕 In 1960, Bristol-Myers Squibb introduced Excedrin Extra Strength for headaches, the first multi-ingredient formulation headache treatment product.〔(【引用サイトリンク】title=New Headache Relief – No Water Needed )〕 Contains 250 mg acetaminophen, 250 mg aspirin and 65 mg caffeine * 1969 Excedrin PM The first headache and sleeping pill combined product.〔 Contains 500 mg acetaminophen and 38 mg diphenhydramine citrate as a sleep aid, the same active ingredients as Tylenol PM, which was introduced several years later. * 1998 Excedrin Migraine At the beginning of 1998, the FDA granted clearance to market Excedrin Migraine for the relief of migraine headache pain and associated symptoms. Excedrin Migraine continued the trend of marketing pain products for specific types of pain, becoming the first migraine headache medication available to consumers without a prescription,〔(【引用サイトリンク】title=Bristol-Myers Squibb News )〕 even though it has identical ''active'' ingredients to the regular Excedrin Extra Strength product, 250 mg acetaminophen, 250 mg aspirin and 65 mg caffeine. In fact, upon the product's launch, its advertising slogan was “Excedrin is now Excedrin Migraine,” noting that the two were the same product. * 2003 Excedrin Tension Headache Contains 500 mg acetaminophen and 65 mg caffeine. * 2005 Excedrin Sinus Headache Contains 325 mg acetaminophen and 5 mg phenylephrine HCl as a decongestant. * 2007 Excedrin Back and Body A dual-ingredient formula claiming that it "works two ways—as a pain reliever and a pain blocker right where it hurts". Contains 250 mg acetaminophen, 250 mg aspirin.〔(【引用サイトリンク】title=Excedrin Back & Body )〕 * () Excedrin Menstrual Complete Excedrin Menstrual Complete continues the trend of marketing pain products for specific types of pain, even though it has identical active ingredients to the regular Excedrin Extra Strength product and Excedrin Migraine, 250 mg acetaminophen, 250 mg aspirin and 65 mg caffeine. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Excedrin (brand)」の詳細全文を読む スポンサード リンク
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